Why You’ll Love This Recipe

Flavorful Layers: Combines savory beef, creamy ranch, and cheesy goodness.
Easy Preparation: Simple steps make it accessible for all cooking levels.
Versatile: Easily adaptable with different proteins or spice levels.
Crowd-Pleaser: Ideal for family dinners or social gatherings.
Make-Ahead Friendly: Can be prepared in advance and baked when needed.

Ingredients

(Tip: You’ll find the full list of ingredients and measurements in the recipe card below.)

1 pound ground beef
1 medium onion, chopped
1 medium bell pepper, chopped
1 (10-ounce) can diced tomatoes with green chilies, drained
1 packet taco seasoning
1 (8-ounce) can refrigerated biscuits
1 cup sour cream
1 cup mayonnaise
1 packet ranch dressing mix
1 cup shredded cheddar cheese
1 cup shredded Monterey Jack cheese
1 (4-ounce) can sliced jalapeños (optional)

Directions

Preheat Oven: Set your oven to 350°F (175°C) and lightly grease a 9×13-inch baking dish.
Cook Beef Mixture: In a large skillet over medium heat, brown the ground beef. Add chopped onion and bell pepper; sauté until softened (about 5–7 minutes). Stir in taco seasoning and drained diced tomatoes with green chilies; cook for an additional 3–5 minutes. Remove from heat.
Prepare Biscuit Base: Press the refrigerated biscuits into an even layer at the bottom of the prepared baking dish. Bake for 5 minutes to prevent a soggy base.
Assemble Casserole: Evenly spread the beef mixture over the partially baked biscuit crust.
Mix Creamy Topping: In a medium bowl, combine sour cream, mayonnaise, and ranch dressing mix. Spread this mixture over the beef layer.
Add Cheese and Jalapeños: Sprinkle shredded cheddar and Monterey Jack cheeses over the top. Add sliced jalapeños if desired.
Bake: Place the assembled casserole in the oven and bake for 30–35 minutes, or until the cheese is melted and bubbly.
Serve: Allow to cool slightly before serving.

Servings and Timing

Servings: 8
Prep Time: 15 minutes
Cook Time: 35 minutes
Total Time: 50 minutes

Variations

Protein Options: Substitute ground turkey or chicken for a lighter version.
Vegetarian: Use plant-based meat alternatives.
Spice Level: Adjust by adding more or fewer jalapeños or using spicy taco seasoning.
Cheese Choices: Experiment with different cheeses like Pepper Jack or Colby.

Storage/Reheating

Refrigeration: Store leftovers in an airtight container in the refrigerator for up to 3 days.
Freezing: Freeze individual portions in freezer-safe containers for up to 3 months. Thaw overnight in the refrigerator before reheating.
Reheating: Warm in the oven at 350°F (175°C) until heated through, or microwave individual portions until hot.

FAQs

What is John Wayne Casserole?

A layered casserole featuring seasoned ground beef, a creamy ranch topping, biscuits, and melted cheese, named after the iconic actor John Wayne.

Can I make this casserole ahead of time?

Yes, assemble the casserole, cover, and refrigerate for up to 24 hours before baking.

How can I make this dish spicier?

Add extra jalapeños, use hot taco seasoning, or include a dash of cayenne pepper.

Is there a vegetarian version?

Yes, substitute the ground beef with plant-based meat alternatives and ensure other ingredients are vegetarian-friendly.

Can I use homemade biscuits?

Absolutely, homemade biscuit dough can replace refrigerated biscuits.

What sides pair well with this casserole?

A fresh green salad, steamed vegetables, or cornbread complement this dish nicely.

How do I store leftovers?

Place in an airtight container and refrigerate for up to 3 days or freeze for up to 3 months.

Can I use different cheeses?

Yes, feel free to experiment with cheeses like Pepper Jack, Colby, or a Mexican blend.

What’s the origin of this recipe?

Originally contributed by John Wayne to a charity cookbook, it has evolved over time into the hearty casserole known today.

Can I add other vegetables?

Certainly, ingredients like corn, black beans, or diced tomatoes can be added for variety.

Conclusion

John Wayne Casserole is a flavorful, comforting dish that’s easy to prepare and sure to satisfy. With its customizable ingredients and hearty layers, it’s a versatile recipe perfect for any occasion. Give it a try and enjoy a taste of classic comfort food.